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Safe and active advanced T cell therapies

We apply our broad array of T cell programming technologies and capabilities to engineer precisely targeted controlled and highly active T cell therapies that are designed to better recognize cancer cells, break down their defense mechanisms and eradicate these cancer cells.

CAR T cell therapies

We use Chimeric Antigen Receptors (CARs) to reprogram our T cell product candidates. These receptors combine the tumor recognition domain of an antibody with the activation and costimulatory domains from the t cell receptor to rearm a patient’s T cells to recognize and kill their cancer cells.

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Pipeline Products

Our next generation, programmed T cell therapies in development.

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Advanced cell programming technology

Autolus is applying its extensive cell programming capability to develop a pipeline of precise, controlled and highly active products.

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Manufacturing

We manufacture our product candidates and commercial supply in the UK.

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Latest Abstracts & Publications

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Blood
August 30 2023

CD19/CD22 targeting with co-transduced CAR T-cells to prevent antigen negative relapse after CAR T-cell therapy of B-ALL

Molecular Therapy Methods & Clinical Development
July 14 2023

Detection and quantification of integrated vector copy number by multiplex droplet digital PCR in dual-transduced CAR T cells

Nature Medicine
July 06 2023

Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia

Chimeric Antigen Receptor T Cell therapy
Advanced cell programming