Our purpose
At the forefront of a revolution in cancer treatment
Chimeric Antigen Receptor (CAR) T cell therapies have been shown to be effective in some hematological malignancies and may have wide applications as a cancer treatment, with the potential for cure in some patients. Autolus uses its rich technology toolbox and expertise to refine and tailor its therapeutic candidates to tackle the indication of interest.
Autolus is a leader in T cell programming, underpinning the broad technology toolbox and manufacturing technology. Autolus is developing cancer therapies which we believe will offer patients substantial benefits over the existing standard of care.
Focused on delivering obe‑cel
A potentially transformational treatment for adult ALL , obe-cel met its primary endpoint at an interim analysis of the phase 2 FELIX study in 2022. Additional data are expected in mid-2023 with a BLA submission to the US FDA planned by the end of 2023. The opportunity for obe-cel extends beyond adult ALL. Obe-cel is currently being investigated in ongoing clinical studies for B-NHL indications and pediatric ALL.
Alongside obe-cel, Autolus are progressing a number of pipeline assets both in preclinical and clinical development across hematological malignancies and solid tumors.
A strong investor base
Autolus has secured funds for the development and filing of obe-cel in relapsed / refractory adult ALL, in addition to preparation for commercialization and the initial manufacturing infrastructure build.
Autolus is focused on developing potentially curative therapies for areas of high unmet need, as well as striving to deliver value for its shareholders.
