Dedicated to every detail that drives CAR T success

Focused on your needs

Developing treatments for patients with cancer and autoimmune disease

Corporate presentations

Clinical-stage programs for hematological and solid tumor indications as well as autoimmune diseases

Transforming treatments for adult Acute Lymphoblastic Leukemia

Our products
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Who we are

Autolus applies extensive programming capabilities to develop advanced autologous T cell therapies that have the potential to deliver life-changing therapies to patients with cancer and autoimmune diseases and is building a fully integrated, next-generation CAR T company

About us

Our Technology

Chimeric Antigen Receptors

We use Chimeric Antigen Receptors (CARs) to reprogram our T cell product candidates. These receptors combine the tumor recognition domain of an antibody with the activation and costimulatory domains from the T cell receptor to rearm a patient’s T cells to recognize and kill their cancer cells.

Advanced Cell Programming

Autolus is applying its extensive cell programming capability to develop a pipeline of precise, controlled and highly active products.

T Cell Manufacturing

We have developed our own proprietary viral vector and semi-automated cell manufacturing processes to engineer a patient's T cells with the CAR and other advanced cell programing modules.

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Abstracts and Publications

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New England Journal of Medicine
November 27 2024

Obecabtagene Autoleucel in Adults with B-Cell Acute Lymphoblastic Leukemia

Nature Medicine
July 06 2023

Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia

Molecular Therapy
March 21 2023

Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Latest news

Get the latest updates from Autolus on new research, company news and events

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Information for patients

Clinical trials are required to gain regulatory approval for new medicines to advance patient care.

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Life at Autolus

Whilst working at Autolus you will enjoy a flexible, diverse and dynamic working environment which actively promotes creativity, leadership and teamwork – together we are ONE Autolus.

Careers at Autolus

Investors

Autolus is building a fully-integrated, next generation CAR T company. It is committed to the development and commercialization of obe-cel in r/r Adult ALL and is progressing opportunities for obe-cel in additional indications alongside its preclinical and clinical pipeline for hematological malignancies and solid tumors.

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Breaking news:

Autolus obtains its first FDA approval for a CAR T cell therapy!

Please note that this CAR T cell therapy is not authorized for use outside of the US. If you are a physician based in the US, please visit this website to learn more about our product.

CAR=chimeric antigen receptor; FDA=Food and Drug Administration.

© Autolus, Inc. 2025. Autolus and associated logo are trademarks of Autolus Therapeutics. All Rights Reserved. 11/2024 US-AUC-0005